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Children 2 months of age and older—Use and dose must be determined by your doctor Treatment. One statin, lovastatin, should definitely be taken with food. Tips May be taken with or without food. It's probably better to take it with food. The risk of side effects may be higher in the elderly. Gabapentin may be given with or without food. May be taken with or without food. The most common serious adverse reactions in participants 16 years of age or older and have at least 3 weeks after the last dose. Three types of angiotensin-converting enzyme (ACE) inhibitors must be taken on an empty stomach. Studies indicate that food has no influence on the effectiveness of the medication. Take only as directed by your doctor and do not share with anyone else as misuse can encourage the development of drug-resistant bacteria and reduce the effectiveness of Bactrim Answer this question Answers MA marjorie zych 4 Jan 2011 I highly suggest taking it with food to prevent nausea. 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